The fonds reflects the scientific and literary outreach activities of the Montreal Natural History Society over the course of its existence and contains correspondence, minutes, financial records, council and committee reports, membership lists, donation lists, catalogues of holdings, newspaper clippings, lecture advertisements and weather maps. In addition, the fonds includes reference material to other societies and information regarding the publication and creation of the Canadian Naturalist and Quarterly Journal of Science, Canadian Naturalist and Geologist and the Canadian Record of Science.

The fonds is composed of the following series: 1) Accounting Records (1860-1917); 2) Administrative Records (1833-1887); 3) Catalogues (ca.1829-ca.1925); 4) Correspondence (1871-1896 with gaps); 5) Essays and Lectures (1829-1852); 6) Minutes (1827-1832,1844-1923); 7) Montreal Microscopical Society (1884-1906); 8) Reports (1828-1881 with gaps); 9) Weather Maps (1895-1897).