Letter to Simon Flexner from William Osler, 13, Norham Gardens, Oxford, Oxfordshire, England. Good wishes on his trip back. Could not get the information asked by Flexner, because Denys was away. Will send the latter's reply. Mentions that he sent the Huxley bronze for Jacobs. Asks him to take a photo of it for the (Rockefeller) Institute and for him to put in the Collected Works. Greetings to Cole and the staff.

Letter to Simon Flexner from William Osler, From the Regius Professor of Medicine, Oxford, Oxfordshire, England. Thanks and compliments on the Journal. Norman Gwyn wrote him that they had discovered the spirochaete in a case of infectious jaundice at the No.1 Canadian General Hospital in France. The figures he gave are identical with the Japanese ones. Mentions that they had a fatal case of it at the Canadian Hospital in Taplow, for which he will have the specimens stained. Civilities.

Letter to Simon Flexner from William Osler, From the Regius Professor of Medicine, Oxford, Oxfordshire, England. Robb writes that Flexner's serum is much more effective. There was something rotten with the stuff they were using in England, which explains the deceiving results. Fortunately, the epidemic is subsiding rapidly. Gordon will have a good report on the bacteriology. About Hort's paper in the British Medical Journal, he gathered from Gordon that he is only a "half-baked" bacteriologist. Cushing is visiting them and gave a sad story about the cases of gas bronchiolitis, of which they are beginning to get some cases. Comments about the Lusitania horror. It will take generations to bridge the present gulf between England and Germany. Civilities.

Letter to Simon Flexner from William Osler, 13, Norham Gardens, Oxford, Oxfordshire, England. Thanks for arranging about Miss Fitzgerald. Suggests to have Mr. Justice Moulton's evidence before the Vivi-Section Committee published in the United States, as a separate campaign pamphlet. Sympathizes with his trouble. Mentions that in England, the people against the vivisection seem to have got into ill odor. Civilities.

Letter to Simon Flexner from William Osler, From the Regius Professor of Medicine, Oxford, Oxfordshire, England. They have trouble with the cerebro-spinal serum, the results are very unsatisfactory. They have used the Lister Institute, the Burroughs and Wellcome, and the Mulford, and did not get any proper serological test. They are now using fresh serums prepared from Canadian organisms, but with no result. They are having no end of trouble in getting the carriers disinfected. Asks him advice, and if he has any new serum prepared on Martha Wollstein's suggestion. The outbreak is spreading.

Letter to Simon Flexner from William Osler, From the Regius Professor of Medicine, Oxford, Oxfordshire, England. Sends him Gordon's letter. The letter follows : Explains that they tried Vedder's starch agar and they are pleased with it. Technical details about his composition. Technical details about the meningococci's reaction with Flexner's serum, Mulford serum and the Pasteur Institute serum. Mentions that the Lister Institute and Burroughs, Wellcome and Co. have been preparing serum from strains from their cases. Robb asks him for cultures for Flexner, but his letter arrived too late, so he wired him to get some from Beattie.

Letter to Simon Flexner from William Osler, From the Regius Professor of Medicine, Oxford, Oxfordshire, England. Informs him that the meningitis has practically gone, with an occasional resurgence, as at Birmingham. Sure that it will come back next winter with the new recruits. Has sent on his note to Gordon, whose work has been most satisfactorily. Robb's results have been excellent. They are settled down to the idea of a protracted war, two or three years at least. Gives his opinion on the strength of Germany. Deplores the gulf that is being dug between such nice people as were so many of their professorial friends and the rest of the world. Revere has gone to France with the McGill Unit. Civilities.

Letter to Simon Flexner from William Osler, 13, Norham Gardens, Oxford, Oxfordshire, England. Acknowledgment of his letter of the 19th (CUS417/126.12). Would love to be with them all next year but he cannot possibly leave. Explains that they are tied up with many activities which are not very essential but it would not be appreciated if he went away for three months. He also dreads the over-warm welcome, and the many visits that would tax his heart too much. Will give him his final decision later. Thanks him for the invitation. Comments on George Draper. Has asked Newsholme to send the latter for a study of the outbreak of encephalitis. Details on the features of the outbreak. Draper said that the cases in Sheffield are of the same type as Heine-Medin. Mentions another outbreak in France where the organism described by Flexner and N. has been found. Asks him to keep it secret as the Bradford's letter was official. Civilities.

Letter to Simon Flexner from William Osler, 13, Norham Gardens, Oxford, Oxfordshire, England. Thanks for a photo. Incites him to put a group of men at work to determine the incidence of syphilis in the newborn, stillborn and the community at large. Deplores the absence of trustworthy figures on the matter. Mentions the hot discussion in England. Osler with others are trying to have the Venereal Disease put under the Public Health authorities. P.S. Acknowledges and thanks for the two Transylvania monographs. Comments on Charles Caldwell.

Letter to Simon Flexner from William Osler, From the Regius Professor of Medicine, Oxford, Oxfordshire, England. Thanks for a photo. Incites him to put a group of men at work to determine the incidence of syphilis in the newborn, stillborn and the community at large. Deplores the absence of trustworthy figures on the matter. Mentions the hot discussion in England. Osler with others are trying to have Venereal Disease put under the Public Health authorities. P.S. Acknowledges and thanks for the two Transylvania monographs. Comments on Charles Caldwell.