The fonds contains chiefly of family correspondence between members of the Penfield and Chester families, as well as clippings and correspondence regarding Wilder Penfield's autobiography "No Man Alone" and correspondence regarding posthumous honours for Wilder Penfield. Family correspondence includes a 1917 letter from Helen Kermott (later Helen Kermott Penfield) accepting Wilder Penfield's marriage proposal. Much of the family correspondence is between Wilder and Helen Penfield and their daughter Priscilla and her husband William M. (Bill) Chester Jr., as well as Bill Chester's parents William (Sr.) and Alice Chester. There are incoming letters and many carbon copies of outgoing letters. A series of 1949 letters congratulates the young couple (Bill Chester and Priscilla Penfield) on their engagement. One letter is also between Wilder Penfield and George Chester. A few materials are related to posthumous honours for Wilder Penfield, such as the naming of a building after him at John Abbott College (letter to Wilder Penfield Jr.) and a 1982 speech given by Priscilla at the Penfield Children's Center (typescript copy). There is also correspondence between Bill Chester and William Feindel. One 1976 carbon copy of a letter (1976) details the period following the death of Priscilla's father, Wilder Penfield, while the couple was in Japan. Materials related to "No Man Alone" include clippings from journals and newspapers of reviews and book announcements, as well as two copies of the book jacket and some related correspondence.

The fonds consists of books, letters, documents, drafts, publications, photographs, and several artifacts collected by W. W. Francis and Marian Francis Kelen over the course of their lifetimes. Many books and documents relate to Sir William Osler and the Osler family including several personal letters, the Deed of Trust documents regarding the Bibliotheca Osleriana, drafts of Osler's works, and a wooden travelling trunk that belonged to Edward Revere Osler. The fonds also includes original poetry written by Marian Osborne, W. W. Francis, and Marian Francis Kelen.

Kiang's papers cover the few years he was employed by McGill. His teaching materials include course outlines and examinations, as well as examination papers for a course in Oriental philosophy he gave at the University of Oregon Summer School in 1930. The administration of the Department of Chinese Studies is documented by requisitions and invoices for equipment and furniture, correspondence on library purchases, and letters regarding possible posts in the department, the curriculum, Kiang's salary and appointment, the Gest Chinese Library and general administrative matters. Kiang's personal files concern his work with the Hung Tao Society, his collaboration with Witter Bynmer, current events in China, and Kiang's publications and speaking engagements.

Fonds consists of the personal and professional papers of Louis and Irene Kon including extensive correspondence between the Kon family. Included are materials relating to the founding of the Norman Bethune Foundation and Bethune memorials; the making of Ted Allan's movie, "Making of a Hero", including the conflict with Syd Gordon regarding creative differences; a manuscript draft and notes on Larry Stephenson's manuscript 'Two Petrals.'

The Lyman-Scrimger Family Fonds consists of the papers of the Lyman, Scrimger and Johnston Families. Reverend John Scrimger's daughter married Walter Ernest Lyman and their daughter, Elizabeth, in turn married Wyatt Galt Johnston. Elizabeth's sister is Mary Minta Turnor.

The Lyman-Scrimger papers largely consist of approximately 42 cm of photographs. Two albums contain family portraits, while two others assembled by Albert Clarence Lyman (B.A., 1878) and Walter E. Lyman (B.A., 1881) also include pictures of McGill classmates. The large collection of unbound photographs contain a number of views of Western Canada taken ca. 1900, Montreal scenes, and travel snapshots taken in Europe (ca. 1905-1910). Two scrapbooks compiled by the Reverend John Scrimger contain newsclippings, poems, cards, letters, photographs, and memorabilia of a family or sentimental nature. The reminder of the papers consists of newsclippings, programmes and so forth related to members of the family as well as a few scattered items of correspondence, probably collected by Mrs. Walter Lyman.

The Johnston Family papers comprise Wyatt Galt Johnston’s laundry lists and grocery accounts, ca. 1899; a letter to Elizabeth Johnston from her mother in Lennoxville, 1906; H. Wyatt Johnston’s school reports, 1907-1911; and letters of sympathy and memorial cards sent to H. Wyatt Johnston on the death of his mother Elizabeth Johnston, 1943 and his aunt Mary Tunor, 1945.

Mary Minta Turnor’s papers consists of correspondence, largely with members of her family in the Eastern Townships on domestic news. A few photographs of houses and pets, as well as some recipes, are also included.

Fonds contains Dr. M.H.F. Friedman's personal papers and files relating to Dr. Boris P. Babkin and also correspondence with the editor of Babkin's biography of I.P. Pavlov.

Family correspondence chiefly from 1763 to 1820 and family history documents.

The fonds contains Margaret Gillett's source materials and drafts for her book Dear Grace, a Romance of History. The source materials include original letters from William C. Little to Grace Ritchie written between 1889-1893.

Consists of an English translation of a letter to the Marquis de la Jonquière written by Antoine-Louis Rouillé, comte de Jouy, secretary of state for the French Navy, at Versailles, dated 28 February 1750. The letter discusses an immediate release of prisoners of war taken during conflicts between the French and British colonies. It also includes a mention of Indigenous allies of England and France, and Indigenous people captured during the conflicts: "the Indian Prisoners among the two Nations be likewise released, but after all the French and English Prisoners are released" The letter also includes the name of examiner Josiah Willard, secretary of the province of Massachusetts-Bay.

The fonds contains materials that Dr. M. Entin collected for his biography of Dr. Archibald. Mainly include articles relate to tuberculosis, pancreatitis, wound healing, history of surgery, and scientific writing. It also includes letters from Edward Archibald to Mrs. Archibald, letters to Archibald from William Osler and Sir Henry Gray, addenda of Archibald's world journey in 1936, and articles by Archibald.

Some draft chapters of the biography of Dr. Archibald and research data for 100th Anniversary of Royal Victoria Hospital can also be found in the fonds.