Charles Stone Bryan was born on January 15, 1942, in Columbia, South Carolina.

He is a retired American physician, researcher, author, medical historian, and Heyward Gibbes Distinguished Professor Emeritus of Internal Medicine at the University of South Carolina, Columbia. He received his higher education at Harvard College, The Johns Hopkins University School of Medicine, and Vanderbilt University Medical Center. In 1974, he returned to Columbia as the first infectious diseases specialist in central South Carolina, where he practiced until his retirement forty-four years later (2018). In 1977, he became a charter faculty member at the USC School of Medicine, where he has served as Director of the Division of Infectious Diseases (1977-1993), Chair of the Department of Medicine (1992-2000), and Director of the Center for Bioethics and Medical Humanities (from 2000). Dr. Bryan's publications include 12 books and monographs, more than 160 articles in peer-reviewed journals, and more than 300 editorials. His writings mainly concern infectious diseases, medical history, medical biography, and various aspects of the humanities as applied to medicine, including the status of medicine as a profession and medical professionalism. As a noted medical historian, he is authority on the life of Dr. William Osler. He published five books related to Osler, e.g., “Osler: Inspirations from a Great Physician” (1997), and many articles in peer-reviewed journals. He is the editor of “Sir William Osler: An Encyclopedia” (2020), intended as a resource for twenty-first-century scholars seeking to re-evaluate Osler’s place in the history of medicine, science, and, more generally, the humanities. He is a recipient of the William Osler Medal of the American Association for the History of Medicine (1967), the Theodore E. Woodward Award of the American Clinical and Climatological Association (2002), the Lifetime Achievement Award of the American Osler Society (2010), and, from the American College of Physicians, the Laureate Award, the Nicholas E. Davies Memorial Scholar Award, and the Centennial Legacy Award. Dr. Bryan is a past president of numerous organizations, including the American Osler Society and is an inductee into the Society of St. Luke (2012) and the Order of the Palmetto (2013), the highest civilian honor in the state of South Carolina, for his lifelong achievements in medical research, infectious disease, and medical education in South Carolina. He is a Master of the American College of Physicians and a Fellow of the Royal College of Physicians of Edinburgh and the Royal College of Physicians of London.

Dr. John Bryant was born on July 8, 1850, in Cohasset, Massachusetts.

He studied at Harvard College (AB 1873) and Harvard Medical School (MD 1878).

In 1878, he married Charlotte Olmstead. He died on March 20, 1908, in Boston, Massachusetts.

Rev. Thomas Bryant was born in 1832, in Kingswood, Gloucestershire, England. In 1858, he married Elizabeth Pitchford (1840–1899) and they had 9 children. He died in March 1899, in Mountain Ash, Monmouthshire, Wales.